The importance of anal cancer screening and high-resolution anoscopy to gastroenterology practice.

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Although human papillomavirus (HPV)-related anal squamous cell cancer (ASCC) is rare, its incidence has been rising and in high-risk populations exceeds the incidence of cancers for which screening programs are […]

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Flexible endoscopic strategies for the difficult esophageal stricture.

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Benign strictures of the esophagus, caused by various causes, are frequently encountered in clinical practice. Although endoscopic dilation is still the standard and first-line therapy, complex and difficult esophageal strictures […]

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Intravenous fluid resuscitation in the management of acute pancreatitis.

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In the absence of proven effective pharmacologic therapy in acute pancreatitis, and given its simplicity, wide availability, and perceived safety, intravenous fluid resuscitation remains the cornerstone in the early treatment […]

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Expanding indications for pancreatic islet cell transplantation.

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We aimed to summarize the current state of performing pancreatic islet autotransplantation (IAT) for indications other than total pancreatectomy for chronic pancreatitis.The current article will review expanded indications for IAT […]

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Management of regurgitation in patients with gastroesophageal reflux disease.

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Precision treatment of medically-refractory regurgitation differs from that of heartburn. Regurgitation is an often-overlooked symptom characterized as a bitter taste in the mouth or a sense of fluid moving up […]

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Endoscopic eradication therapy for Barrett’s oesophagus: state of the art.

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Barrett’s oesophagus is the only identifiable precursor lesion to oesophageal adenocarcinoma. The stepwise progression of Barrett’s oesophagus to dysplasia and invasive carcinoma provides the opportunity to intervene and reduce the […]

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How to advise patients on the risk of chronic proton pump inhibitor therapy.

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Proton pump inhibitors (PPIs) are widely prescribed and have excellent short-term tolerability. Administrative database studies have highlighted that many diseases are associated with PPI therapy including pneumonia, fracture, cardiovascular disease, […]

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The management of the hospitalized ulcerative colitis patient: the medical-surgical conundrum.

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In this review article, we address emerging evidence for the medical and surgical treatment of the hospitalized patient with ulcerative colitis.Ulcerative colitis is a chronic inflammatory disease involving the colon […]

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Magnetic sphincter augmentation versus fundoplication for gastroesophageal reflux disease: pros and cons.

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The purpose of this magnetic sphincter augmentation (MSA) year in review article is to provide a clear understanding for the current state of MSA literature in 2019, and contrast MSA […]

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Fatigue in inflammatory bowel disease: a problematic ailment.

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Fatigue, a protean complaint encompassing both physical, mental exhaustion but also demotivation, has shown to effect quality of life in patients with inflammatory bowel disease (IBD). Here we present a […]

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EsoFLIP for esophageal dilation: proposed advantages.

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The EsoFLIP integrates impedance planimetry technology into a dilator balloon capable of dilating from diameters between 10 and 30 mm via controlled volumetric distension while providing real-time visualization and objective measurement […]

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The burden of cost in inflammatory bowel disease: a medical economic perspective.

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The cost of care for inflammatory bowel disease (IBD) has nearly doubled over the last two decades. With evolving treatment paradigms utilizing costly but efficacious biologic agents earlier and more […]

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Integration of telemedicine into clinical practice for inflammatory bowel disease.

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In the context of the rising incidence and complexity of inflammatory bowel disease (IBD), telehealth offers new ways to support remote and efficient delivery of healthcare services. The aim of […]

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Approaches to diet therapy for eosinophilic esophagitis.

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The aim of this review is to highlight recent advances in dietary therapy for eosinophilic esophagitis (EoE).An empiric elimination diet step-up strategy is now well established as the initial approach […]

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Gaining resilience and reducing stress in the age of COVID-19.

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The world is experiencing the evolving situation associated with the outbreak of the Corona Virus Disease-2019 (COVID-19) virus, and there is more of need than ever for stress management and […]

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Opioid-induced esophageal dysfunction.

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Chronic opioid use is common and can cause opioid-induced esophageal dysfunction (OIED). We will discuss the pathophysiology, diagnosis, and management of OIED.OIED is diagnosed based on symptoms, opioid use, and […]

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Postoperative Crohn’s disease management.

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Despite multiple advances in the medical treatment of Crohn’s disease, it is recognized that a significant proportion of patients will ultimately require surgical resection at some point during their disease […]

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Radiation enteritis: from diagnosis to management.

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As cancer treatments improve more patients than ever are living for longer with the side effects of these treatments. Radiation enteritis is a heterogenous condition with significant morbidity. The present […]

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New systemic agents for hepatocellular carcinoma: an update 2020.

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Despite major therapeutic improvements in most cancer entities, hepatocellular carcinoma (HCC) has remained a dismal disease. In fact, incidence and mortality are increasing in many parts of the world, including […]

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Hepatic manifestations of cystic fibrosis.

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Liver disease in cystic fibrosis (CF) usually develops before puberty, is often asymptomatic and slowly progressive. Multilobular cirrhosis develops in approximately 5-10% of patients by the age of 18, and […]

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The utility of liver biopsy in 2020.

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Over the past decade, imaging modalities and serological tests have emerged as important tools in the evaluation of liver diseases, in many cases supplanting the use of liver biopsy and […]

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Protein-losing enteropathy.

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The present review offers its readers a practical overview of protein-losing enteropathy, particularly with regard to diagnostic and therapeutic approaches. The aim is to support clinicians in their daily practice […]

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