The Resource Use Inflection Point for Safe NICU Discharge.

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(1) To identify a resource use inflection point (RU-IP) beyond which patients in the NICU no longer received NICU-level care, (2) to quantify variability between hospitals in patient-days beyond the […]

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Test Strategies to Predict Inflammatory Bowel Disease Among Children With Nonbloody Diarrhea.

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We evaluated 4 diagnostic strategies to predict the presence of inflammatory bowel disease (IBD) in children who present with chronic nonbloody diarrhea and abdominal pain.We conducted a prospective cohort study […]

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Linking the duodenal microbiota to stunting in a cohort of undernourished Bangladeshi children with enteropathy.

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Environmental enteric dysfunction (EED) is an enigmatic disorder of the small intestine postulated to play a role in childhood undernutrition, a pressing global health problem. Defining the incidence of EED, […]

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Timing of liver transplantation for pediatric acute liver failure due to mushroom poisoning: a case report and literature review.

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Pediatric acute liver failure is a rare, life-threatening illness. Mushroom poisoning is a rare etiology. For patients with irreversible pediatric acute liver failure, liver transplantation is the ultimate lifesaving therapy. […]

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Long-Acting Reversible Contraception: Specific Issues for Adolescents.

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Long-acting reversible contraceptives are the most effective methods to prevent pregnancy and also offer noncontraceptive benefits such as reducing menstrual blood flow and dysmenorrhea. The safety and efficacy of long-acting […]

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Barrier Protection Use by Adolescents During Sexual Activity.

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Rates of sexual activity, pregnancies, and births among adolescents have continued to decline during the past decade to historic lows. Despite these positive trends, many adolescents remain at risk for […]

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Barrier Protection Use by Adolescents During Sexual Activity.

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Rates of sexual activity, pregnancies, and births among adolescents have continued to decline during the past decade to historic lows. Despite these positive trends, many adolescents remain at risk for […]

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Race, Postoperative Complications, and Death in Apparently Healthy Children.

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That African American (AA) patients have poorer surgical outcomes compared with their white peers is established. The prevailing presumption is that these disparities operate within the context of a higher […]

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Cardiac-associated biliary atresia (CABA): a prognostic subgroup.

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To describe the range of concurrent cardiac malformations in biliary atresia (BA) while providing a functional framework of risk.Demographic and variables were collected from a prospectively maintained single-centre database. Infants […]

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Vitamin D toxicity in a pediatric toxicological referral center; a cross-sectional study from Iran.

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Vitamin D is an essential element for body health with its supplements generally administered to prevent vitamin D deficiency. Since these supplements are available in domestic settings, vitamin D toxicity […]

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Cardiorespiratory and Pulse Oximetry Monitoring in Hospitalized Children: A Delphi Process.

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Cardiorespiratory and pulse oximetry monitoring in children who are hospitalized should balance benefits of detecting deterioration with potential harms of alarm fatigue. We developed recommendations for monitoring outside the ICU […]

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Ruxolitinib in Alleviating the Cytokine Storm of Hemophagocytic Lymphohistiocytosis.

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Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening syndrome classified into primary HLH and secondary HLH. Secondary HLH is always caused by autoimmune disease, infections, or cancer. The first-line therapy […]

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Changes in the UK baby food market surveyed in 2013 and 2019: the rise of baby snacks and sweet/savoury foods.

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To assess how the baby food market in the UK has changed between 2013 and 2019.United Kingdom.A cross-sectional survey of all infant food products available to buy in the UK […]

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Parental Perspectives on Continuous Pulse Oximetry Use in Bronchiolitis Hospitalizations.

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Because of the impact of continuous pulse oximetry (CPOX) on the overdiagnosis of hypoxemia in bronchiolitis, the American Academy of Pediatrics and the Choosing Wisely campaign have issued recommendations for […]

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Encephalitis due to herpes zoster without rash in an immunocompetent 12-year-old girl: case report and review of the literature.

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Neurological complications due to reactivation of varicella-zoster virus (VZV) are very uncommon in immunocompetent patients. Generally a vesicular rash is present on one or more dermatomes, preceding or following the […]

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Homozygous GDF2-Related Hereditary Hemorrhagic Telangiectasia in a Chinese Family.

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Hereditary hemorrhagic telangiectasia (HHT) can be clinically diagnosed, but children often lack characteristic features. We report a family with homozygous growth differentiation factor 2 (GDF2)-related HHT diagnosed by genetic testing. […]

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Childhood Urinary Tract Infections and Pregnancy-Related Complications in Adult Women.

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Long-term outcomes of urinary tract infection (UTI) in childhood are not well known. Pregnancy may reveal latent renal damage caused by a UTI because of stress on the kidneys.Our cohort […]

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FEEding DURing red cell transfusion (FEEDUR RCT): a multi-arm randomised controlled trial.

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Necrotising Enterocolitis (NEC) is a devastating neonatal disease. A temporal association between red cell transfusion and NEC has been recognized and there have been concerns about the effects of feeding […]

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Familiarity with the clinical environment, achieved by priming, improves time to antibiotic administration in a simulated paediatric sepsis scenario: a randomised control trial.

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The early administration of antibiotics in sepsis reduces mortality and improves outcomes. This randomised control trial evaluated the effect of environmental priming (EP) on healthcare student performance in a simulated […]

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Transmitted Home Oximetry and Duration of Home Oxygen in Premature Infants.

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To determine if a home oxygen therapy (HOT) management strategy that includes analysis of recorded home oximetry (RHO) data, compared with standard monthly clinic visit assessments, reduces duration of HOT […]

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Quality control of bedside DR in neonatal chest radiography using a chest stabilization device and its clinical application.

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To develop a method for movement control during radiation exposure and to improve image quality of bedside thoracic DR in neonates.Total 60 cases of neonates’ thoracic DR X-ray images, which […]

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Disability and visual outcomes following suspected abusive head trauma in children under 2 years.

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To report disability and visual outcomes following suspected abusive head trauma (AHT) in children under 2 years.We present a retrospective case series (1995-2017) of children with suspected AHT aged ≤24 […]

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Global incidence of Necrotizing Enterocolitis: a systematic review and Meta-analysis.

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Necrotizing Enterocolitis (NEC) is a major cause of morbidity and mortality in the Neonatal Intensive Care Unit (NICU), yet the global incidence of NEC has not been systematically evaluated. We […]

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Effect of Maternal Docosahexaenoic Acid Supplementation on Bronchopulmonary Dysplasia-Free Survival in Breastfed Preterm Infants: A Randomized Clinical Trial.

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Maternal docosahexaenoic acid (DHA) supplementation may prevent bronchopulmonary dysplasia, but evidence remains inconclusive.To determine whether maternal DHA supplementation during the neonatal period improves bronchopulmonary dysplasia-free survival in breastfed infants born […]

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“The right time is just after birth”: acceptability of point-of-care birth testing in Eswatini: qualitative results from infant caregivers, health care workers, and policymakers.

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Testing for HIV at birth has the potential to identify infants infected in utero, and allows for the possibility of beginning treatment immediately after birth; point of care (POC) testing […]

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Pediatric provider perspectives and practices regarding health policy discussions with families: a mixed methods study.

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Advocacy regarding child health policy is a core tenet of pediatrics. Previous research has demonstrated that most pediatric providers believe collective advocacy and political involvement are essential aspects of their […]

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Neurodevelopmental outcome and respiratory management of congenital central hypoventilation syndrome: a retrospective study.

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Congenital central hypoventilation syndrome (CCHS) is a rare disease characterized by sleep apnea. Anoxia often occurs soon after birth, and it is important to prevent anoxia-mediated central nervous system complications; […]

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