A systematic review on the use of Misoprostol at the time of open myomectomy.

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Leiomyomata are common benign pelvic masses that occur in up to 77% of reproductive aged women (Flyckt et al Clin Obstet Gynecol 2017;60(2):252-272). Myomectomies are frequently performed for symptomatic leiomyoma […]

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Low-Grade Endometrial Stromal Sarcoma Diagnosed 8 Years After Hysterectomy With Morcellation.

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Morcellation at the time of minimally invasive hysterectomy or myomectomy for presumed benign indications carries a risk of disseminating undiagnosed uterine malignancies.A 57-year-old woman with a remote history of laparoscopic […]

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Misoprostol for open myomectomy: a systematic review and meta-analysis of randomised control trials.

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Excessive blood loss is a significant risk of myomectomy with the potential need for hysterectomy.To study the effectiveness of preoperative misoprostol compared to placebo at open myomectomy on intra- and […]

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Post-operative Hormonal Treatment for Prevention of Endometrioma Recurrence after Ovarian Cystectomy: A Systematic Review and Network Meta-Analysis.

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The efficacy of hormonal regimens for the prevention of endometrioma recurrence in women who have undergone conservative surgery is still controversial.To compare the efficacy of different hormonal regimens in this […]

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Essentials in Minimally Invasive Gynecology Manual Skills Construct Validation Trial.

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To establish validity evidence for the Essentials in Minimally Invasive Gynecology laparoscopic and hysteroscopic simulation systems.A prospective cohort study was IRB approved and conducted at 15 sites in the United […]

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Platelet activation and placenta-mediated adverse pregnancy outcomes: an ancillary study to the EAGeR trial.

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Platelet activation may play a role in the pathophysiology of placenta-mediated obstetric complications, as evidenced by the efficacy of aspirin for preventing preeclampsia, but published data regarding the relationship between […]

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What do we do when new fibroids form following myomectomy?

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Evidence reports have detailed the shocking lack of high quality data regarding treatment outcomes for uterine fibroids. Moreover, despite the high risk of having new fibroid symptoms following an initial […]

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Comparison of high-intensity focused ultrasound ablation and secondary myomectomy for recurrent symptomatic uterine fibroids following myomectomy: A retrospective study.

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To compare the long-term symptoms alleviation and re-intervention of high-intensity focused ultrasound (HIFU) ablation and secondary myomectomy for women with recurrent symptomatic uterine fibroids following myomectomy.A retrospective analysis.A general hospital […]

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Connecting reproductive health to women’s health with longitudinal research.

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Epidemiologists and social scientists have long utilised longitudinal study designs to examine the associations between exposures, behaviours, health conditions/diagnoses and longer term outcomes. Attention increasingly focuses on pregnancy-related conditions and […]

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Reproductive services for women at high risk for maternal mortality: a report of the workshop of the Society for Maternal-Fetal Medicine, the American College of Obstetricians and Gynecologists, the Fellowship in Family Planning, and the Society of Family Planning.

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Click here to read the full article @ American Journal of Obstetrics and Gynecology

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Intraoperative Tranexamic Acid to Decrease Blood Loss During Myomectomy: A Randomized Double-Blind Placebo Controlled Trial.

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Myomectomy is associated with a significant risk of hemorrhage. Tranexamic acid is a synthetic lysine derivative with antifibrinolytic activity used in other surgical disciplines to reduce blood loss during surgery. […]

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Maternal risk factors and adverse birth outcomes associated with HELLP syndrome: a population-based study.

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We assessed the incidence, risk factors and adverse birth outcomes associated with elevated liver enzymes and low platelets (HELLP) syndrome.A retrospective population-based cohort study.Canada (excluding Quebec), 2012/13-2015/16.Mothers with a singleton hospital […]

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Breakdown in the Expedited Partner Therapy Treatment Cascade: From Reproductive Healthcare Provider to the Pharmacist.

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The rising incidence rates of sexually transmitted infections (STI) in the U.S. highlight the need for concurrent treatment of patients and their sexual partners. Expedited partner therapy (EPT) allows healthcare […]

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Atypical endometrial polyps and the incidence of endometrial cancer: a retrospective cohort study.

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The aim of this study is to evaluate the incidence of endometrial carcinoma, proven after hysterectomy, in patients diagnosed with atypical endometrial hyperplasia confined to a polyp. A secondary aim […]

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Reproductive and hormonal factors and risk of cognitive impairment among Singapore Chinese women.

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Epidemiologic studies suggest that declining estrogen level in menopause may play an important role in the pathogenesis of dementia and contribute to increased risk of cognitive impairment in women. Most […]

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Prediction of pregnancy loss by early first trimester ultrasound characteristics.

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Pregnancy loss prediction based on routinely measured ultrasound characteristics is generally aimed towards distinguishing nonviability. Physicians also use ultrasound indicators for patient counseling, and in some cases to decide upon […]

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Time trends in placenta-mediated pregnancy complications after assisted reproductive technology in the Nordic countries.

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The use of assisted reproductive technology (ART) is increasing worldwide and conception after assisted reproduction currently comprises 3-6% of birth cohorts in the Nordic countries. The risk of placenta-mediated pregnancy […]

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The Use of Hysteroscopy for the Diagnosis and Treatment of Intrauterine Pathology: ACOG Committee Opinion, Number 800.

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This Committee Opinion provides guidance on the current uses of hysteroscopy in the office and the operating room for the diagnosis and treatment of intrauterine pathology and the potential associated […]

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The Use of Hysteroscopy for the Diagnosis and Treatment of Intrauterine Pathology: ACOG Committee Opinion Summary, Number 800.

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This Committee Opinion provides guidance on the current uses of hysteroscopy in the office and the operating room for the diagnosis and treatment of intrauterine pathology and the potential associated […]

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Cardio-metabolic risk factors among young infertile women: a systematic review and meta-analysis.

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There is currently no concise systematic review or meta-analysis addressing cardio-metabolic risk factors in women experiencing infertility.To determine whether infertile women have higher levels of cardiovascular risk factors compared to […]

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Surrogacy Laws in the United States: What Obstetrician-Gynecologists Need to Know.

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The first child carried by a surrogate after in vitro fertilization in the United States was born in 1985. Since then, the number of such births has steadily grown. According […]

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Quality of periconceptional dietary intake and maternal and neonatal outcomes.

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Periconceptional diet quality is commonly suboptimal and sociodemographic disparities in diet quality exist. However, it is unknown whether individual periconceptional diet quality is associated with obstetric outcomes.Our objective was to […]

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Endometriosis Fertility Index for Predicting Non-assisted Reproductive Technology Pregnancy after Endometriosis Surgery: A Systematic Review and Meta-analysis.

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Results of studies that have assessed the accuracy of the Endometriosis Fertility Index (EFI) for predicting non-assisted reproductive technology (ART) pregnancy are inconsistent.We intended to evaluate the accuracy of EFI […]

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Metformin plus Megestrol Acetate (MA) compared with MA alone as fertility-sparing treatment in patients with atypical endometrial hyperplasia and well differentiated endometrial cancer: a randomised controlled trial.

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To assess the efficacy of metformin in megestrol acetate (MA)-based fertility-sparing treatment for patients with atypical endometrial hyperplasia (AEH) and endometrioid endometrial cancer (EEC).A randomized, single-center, open-label and controlled trial […]

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FERTILITY INTENTIONS AND LONG-ACTING REVERSIBLE CONTRACEPTIVE USE AMONG HIV-NEGATIVE SINGLE MOTHERS IN ZAMBIA: Fertility intent and LARC use in Zambia.

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Integrating family planning interventions with HIV studies in developing countries has been shown to prevent mother-to-child HIV transmission and simultaneously reduce HIV and unintended pregnancy in high-risk populations. As part […]

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An economic analysis of preimplantation genetic testing for aneuploidy (PGT-A) by polar body biopsy in advanced maternal age.

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What are the cost per live birth and the incremental cost of preventing a miscarriage with preimplantation genetic testing for aneuploidy (PGT-A) by polar body biopsy and array-based comprehensive genome […]

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Sexual and Reproductive Health Characteristics of Women in Substance Use Treatment in Michigan.

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To evaluate the sexual and reproductive health characteristics of women in treatment for opioid use disorder in Michigan and explore services provided and desired.We conducted a cross-sectional study of female […]

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Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A Randomized Clinical Trial.

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Dietary supplements marketed for male fertility commonly contain folic acid and zinc based on limited prior evidence for improving semen quality. However, no large-scale trial has examined the efficacy of […]

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From 2646 to 15: differentially regulated miRNAs between progenitors from normal myometrium and leiomyoma.

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Uterine leiomyomas (fibroids) are smooth muscle neoplasms of the myometrial layer of the uterus and the most common benign tumors in women. Although their etiology is still unclear, progenitor cells […]

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Reproductive justice for those affected by childhood abuse.

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Pregnancy and childbirth are part of people’s sexual lives and their intimate relationships. When one or both of these have been characterised by violence and/or unpredictability in a person’s childhood, […]

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