TOWARDS PERSONALIZED MANAGEMENT OF CHRONIC HYPERTENSION IN PREGNANCY.

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Chronic hypertension complicates 1-2% of pregnancies and it is increasingly common. Women with chronic hypertension are easily-recognized and in touch with a wide variety of healthcare providers before, during, and […]

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Weight Loss Prior to Pregnancy and Subsequent Gestational Weight Gain: Prepare, a Randomized Clinical Trial.

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Women with elevated body mass index are encouraged to lose weight before pregnancy, but no trials have tested the effects of pre-pregnancy weight loss on health outcomes. Our objective was […]

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Core outcome sets are valuable, but methodological evidence can improve robustness.

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A core outcome set (COS) is the agreed minimum set of outcomes to be measured in studies regarding a specific topic. A COS is considered to encompass the most relevant […]

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When to expect the unexpected: uterine rupture before onset of labour.

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Uterine rupture is a feared complication when a woman with a uterus scarred by a caesarean section (CS) is in labour. The increased awareness of the possibility of uterine rupture […]

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Association of Obstetric and Neonatal Outcomes With Deviation From Guidelines for Gestational Carriers.

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To evaluate whether deviation from American Society for Reproductive Medicine (ASRM) safety guidelines for women who are gestational carriers is associated with increased risk of severe obstetric and perinatal morbidity […]

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Breast cancer risk after hysterectomy with and without salpingo-oophorectomy for benign indications.

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Breast cancer risk has been extensively studied in women with genetic predisposition, i.e. BRCA1/2. Though there are guidelines for performing bilateral salpingo-oophorectomies in individuals with specific genetic risks, oophorectomies are […]

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Early Pregnancy Blood Pressure Elevations and Risk for Maternal and Neonatal Morbidity.

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To investigate whether women with early pregnancy elevated blood pressure (BP) or stage 1 hypertension exhibit increased risk of preeclampsia and maternal or neonatal morbidity.We conducted a clinical cohort study […]

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Postmenopausal Pregnancy in the Era of Assisted Reproductive Technologies.

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Assisted reproductive technologies allow women to achieve pregnancy at ages beyond the limits of their natural reproductive lifespans. As women seek pregnancy later in life, physicians are challenged with balancing […]

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THE MID-LIFE TRANSITION AND THE RISK OF CARDIOVASCULAR DISEASE AND CANCER II: STRATEGIES TO MAXIMIZE QUALITY OF LIFE AND LIMIT DYSFUNCTION AND DISEASE.

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Chronic dysfunction, disabilities and complex diseases such as cardiovascular disease, Diabetes Mellitus Type 2, osteoporosis and certain cancers among other burdens emerge and accelerate in midlife women. Previously in Part […]

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Special Ambulatory Gynecologic Considerations in the Era of COVID-19 and Implications for Future Practice.

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The COVID-19 pandemic has altered medical practice in unprecedented ways. While much of the emphasis in obstetrics and gynecology to date has been on the as yet uncertain impacts of […]

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Counseling and surveillance of obstetric risks for female childhood, adolescent, and young adult cancer survivors: recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group.

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Female childhood, adolescent, and young adult (CAYA) cancer survivors have an increased risk of adverse pregnancy outcomes related to their cancer or treatment-associated sequelae. Optimal care for CAYA cancer survivors […]

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Genital TB screening at an academic fertility center in the US.

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Infertility is a common presentation of female genital tuberculosis (FGTB) in endemic areas. FGTB-related maternal and neonatal complications have increased in recent years following assisted-reproductive technology treatments. Despite rising emigration […]

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A systematic review of the psychosocial impact of fibroids before and after treatment.

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Despite the high prevalence of uterine fibroids, the psychosocial impact of fibroids has not been evaluated across different quality of life indicators and compared to other chronic conditions. Here we […]

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Executive Summary of the Early-Onset Breast Cancer Evidence Review Conference.

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The Centers for Disease Control and Prevention launched the Bring Your Brave campaign to increase knowledge about early-onset breast cancer, defined as breast cancer in women aged 18-45 years. The […]

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Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin Summary, Number 222.

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Hypertensive disorders of pregnancy constitute one of the leading causes of maternal and perinatal mortality worldwide. It has been estimated that preeclampsia complicates 2-8% of pregnancies globally (). In Latin […]

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Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222.

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Hypertensive disorders of pregnancy constitute one of the leading causes of maternal and perinatal mortality worldwide. It has been estimated that preeclampsia complicates 2-8% of pregnancies globally (). In Latin […]

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Intrapartum-related perinatal deaths in births planned in midwifery-led settings in Great Britain: findings and recommendations from the ESMiE confidential enquiry.

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To review quality of care in births planned in midwifery-led settings, resulting in an intrapartum-related perinatal death.Confidential enquiry SETTING: England, Scotland and Wales SAMPLE: Intrapartum stillbirths and intrapartum-related neonatal deaths […]

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A core outcome set for pre-eclampsia research: An international consensus development study.

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To develop a core outcome set for pre-eclampsia.Consensus development study.International.Two hundred and eight one healthcare professionals, 41 researchers, and 110 patients, representing 56 countries, participated METHODS: Modified Delphi method and […]

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Study To Reduce Infection Prior to Elective Cesarean Deliveries (STRIPES): A randomized clinical trial of chlorhexidine.

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Surgical site infections after cesarean delivery are a source of maternal morbidity and usually due to skin microbial flora. Preadmission application of chlorhexidine gluconate via impregnated cloths may decrease surgical […]

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Society for Maternal-Fetal Medicine (SMFM) Consult Series #51: Thromboembolism Prophylaxis for Cesarean Delivery.

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Venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. The risk of VTE is particularly elevated during the postpartum period and especially following cesarean delivery. There is […]

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Association of the First 1,000 Days Systems-Change Intervention on Maternal Gestational Weight Gain.

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To examine the associations of a clinical and public health systems-change intervention on the prevalence of excess gestational weight gain among high-risk, low-income women.In a quasi-experimental trial, we compared the […]

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Challenges in economic evaluations in obstetric care: a scoping review and expert opinion.

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The aim of this study is to identify items of economic evaluation guidelines that are frequently not complied within obstetric economic evaluations and to search for reasons for non-adherence.Scoping review […]

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Consumption of Non-Nutritive Sweeteners in Pregnancy.

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In effort to reduce sugar consumption to prevent diabetes mellitus and cardiovascular diseases, “sugar-free” or “no added sugar” products that substitute sugar with non-nutritive sweeteners (NNS e.g. Splenda, Sweet N’ […]

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Risk assessment of endometrial cancer and endometrial intraepithelial neoplasia in women with abnormal bleeding and implications for clinical management algorithms.

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Most endometrial cancer cases are preceded by abnormal uterine bleeding, offering a potential opportunity for early detection and cure of endometrial cancer. While clinical guidelines exist for diagnostic workup of […]

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A core outcome set for future endometriosis research: an international consensus development study.

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To develop a core outcome set for endometriosis.Consensus development study.International.One hundred and sixteen healthcare professionals, 31 researchers, and 206 patient representatives.Modified Delphi method and modified nominal group technique.The final core […]

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Impact of the ACOG guideline regarding low dose aspirin for prevention of superimposed preeclampsia in women with chronic hypertension.

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Patients with chronic hypertension are at increased risk for superimposed preeclampsia. The 2016 American College of Obstetricians and Gynecologists (ACOG) guideline recommended initiating 81 mg daily aspirin for all pregnant […]

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Pain Management for Medical and Surgical Abortion Between 13 and 24 Weeks Gestation: A Systematic Review.

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High-quality abortion care requires pain be effectively managed, however practices differ, and available guidelines do not specify optimal strategies.To guide providers in effective pain management for second-trimester medical and surgical […]

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Black and Hispanic women are less likely than White women to receive guideline-concordant endometrial cancer treatment.

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Differences in receipt of guideline-concordant treatment might underlie well-established racial disparities in endometrial cancer mortality.Using the National Cancer Database, we assessed the hypothesis that among women with endometrioid endometrial cancer, […]

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Impact on perinatal health and cost-effectiveness of risk-based care in obstetrics: a before after study.

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Obstetric healthcare relies on an adequate antepartum risk selection. Most guidelines used for risk stratification, however, do not assess absolute risks. In 2017, a prediction tool was implemented in a […]

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Impact of Quality of Care on Racial Disparities in Survival for Endometrial Cancer.

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Black women experience poorer survival compared to white women across all endometrial cancer stages and histologies. The incidence of endometrial cancer is 30% lower in black women compared to white […]

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