Protecting higher education institutions from COVID-19: insights from an Italian experience.

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Higher education institutions (HEIs) worldwide have been deeply affected by the Coronavirus Disease 2019 (COVID-19) pandemic and subsequent lockdown measures. HEIs are environments at high risk of COVID-19 diffusion, due […]

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Effect of meteorological parameters on spread of COVID-19 in India and air quality during lockdown.

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The novel Coronavirus (COVID-19) was identified in Wuhan, Hubei Province, China, in December 2019 and has created a medical emergency worldwide. In India, it is already reported more than 855 […]

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Associations between metabolic syndrome and urinary Na-to-K ratio and glomerular filtration rate in middle-aged adults regardless of Na and K intakes.

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Intake of Na-to-K ratio (I-Na/K), urinary Na-to-K ratio (U-Na/K), and estimated glomerular filtration rate (GFR) have been reported to be risk factors of metabolic syndrome (MetS), but results are inconsistent. […]

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No clear association emerges between intergenerational relationships and COVID-19 fatality rates from macro-level analyses.

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The severe acute respiratory syndrome coronavirus 2 originated in Wuhan, China at the end of 2019 and rapidly spread in more than 100 countries. Researchers in different fields have been […]

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Pharmacologic and psychological interventions for depression treatment in patients with kidney disease.

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It remains controversial whether existing therapies, including pharmacologic and psychological interventions, are effective for treatment of depression in patients with chronic kidney disease (CKD) and end-stage kidney disease.Most studies of […]

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Remyelination in multiple sclerosis: from basic science to clinical translation.

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The treatment of multiple sclerosis has been transformed by the successful development of immunotherapies that efficiently reduce disease activity and related clinical relapses during the relapsing-remitting phase of the disease. […]

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Supportive and palliative care for people with respiratory problems and preexisting serious mental illness.

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People living with serious mental illness are at a higher risk of developing respiratory problems that can lead to increased morbidity and early mortality. This review aimed to identify recent […]

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Thermal Nerve Radiofrequency Ablation for the Nonsurgical Treatment of Knee Osteoarthritis: A Systematic Literature Review.

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There are roughly 14 million adults in the United States presenting with symptomatic osteoarthritis (OA) of the knee. Nerve radiofrequency ablation (RFA) is a nonsurgical procedure for the management of […]

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Burosumab in X-linked hypophosphatemia and perspective for chronic kidney disease.

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Perturbations in phosphate and vitamin D homeostasis impacts skeletal health in children and adults. Study of inherited and acquired hypophosphatemic syndromes led to the discovery of fibroblast growth factor 23 […]

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Artificial intelligence mobile health platform for early detection of COVID-19 in quarantine subjects using a wearable biosensor: protocol for a randomised controlled trial.

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There is an outbreak of COVID-19 worldwide. As there is no effective therapy or vaccine yet, rigorous implementation of traditional public health measures such as isolation and quarantine remains the […]

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Population Point Prevalence of SARS-CoV-2 Infection Based on a Statewide Random Sample – Indiana, April 25-29, 2020.

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Population prevalence of persons infected with SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), varies by subpopulation and locality. U.S. studies of SARS-CoV-2 infection have examined infections in nonrandom […]

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Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial.

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This ongoing Phase-2, randomised, placebo-controlled, double-blind study evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood-onset systemic lupus erythematosus (cSLE).Patients (5 to 17 years) were randomised to belimumab […]

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COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2.

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The coronavirus disease 2019 (COVID-19) pandemic continues to pose a global threat to the human population. Identifying animal species susceptible to infection with the SARS-CoV-2/HCoV-19 pathogen is essential for controlling […]

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Neurosurgical Procedures and Safety During the COVID-19 Pandemic: A Case-Control Multi-Center Study.

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Quantitative documentation of the effects of outbreaks, including the COVID-19 pandemic, is limited in the field of neurosurgery. Our study aimed to evaluate the effects of the COVID-19 pandemic on […]

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Efficacy and safety of Sandoz biosimilar rituximab for active rheumatoid arthritis: 52-week results from the randomized controlled ASSIST-RA trial.

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This report provides data for the extent of B cell depletion and recovery, efficacy, safety and immunogenicity of Sandoz rituximab (SDZ-RTX; GP2013; Rixathon®) compared with reference rituximab (Ref-RTX) up to […]

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The Resource Use Inflection Point for Safe NICU Discharge.

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(1) To identify a resource use inflection point (RU-IP) beyond which patients in the NICU no longer received NICU-level care, (2) to quantify variability between hospitals in patient-days beyond the […]

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Estimated County-Level Prevalence of Selected Underlying Medical Conditions Associated with Increased Risk for Severe COVID-19 Illness – United States, 2018.

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Risk for severe coronavirus disease 2019 (COVID-19)-associated illness (illness requiring hospitalization, intensive care unit [ICU] admission, mechanical ventilation, or resulting in death) increases with increasing age as well as presence […]

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Supportive and palliative care of adults with respiratory problems experiencing structural vulnerability from homelessness, prison or other criminal justice system involvement.

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This review seeks to identify the current prevalence of potentially life-limiting respiratory conditions among those who have experienced homelessness, incarceration or had criminal justice involvement, and current developments in, and […]

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Respiratory viral sepsis: epidemiology, pathophysiology, diagnosis and treatment.

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According to the Third International Consensus Definition for Sepsis and Septic Shock, sepsis is a life-threatening organ dysfunction resulting from dysregulated host responses to infection. Epidemiological data about sepsis from […]

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The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study.

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Since a national lockdown was introduced across the UK in March, 2020, in response to the COVID-19 pandemic, cancer screening has been suspended, routine diagnostic work deferred, and only urgent […]

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Comparison of long-term rotational stability of three commonly implanted intraocular lenses.

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To compare rotational stability and its influencing factors in 3 different widely used hydrophobic acrylic intraocular lenses (IOL) from end of surgery (EoS) to 4 to 7 months (6m) in […]

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Risk Factors for Reoperation Following Final Fusion After the Treatment of Early-Onset Scoliosis with Traditional Growing Rods.

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Although there is a high rate of reoperation after final fusion following the treatment of early-onset scoliosis with use of traditional growing rods, the risk factors for reoperation are unknown. […]

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Safety and efficacy of fluoxetine on functional recovery after acute stroke (EFFECTS): a randomised, double-blind, placebo-controlled trial.

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Studies have suggested that fluoxetine could improve neurological recovery after stroke. The Efficacy oF Fluoxetine-a randomisEd Controlled Trial in Stroke (EFFECTS) trial aimed to assess whether administration of oral fluoxetine […]

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Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease.

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To explore whether variability in dietary cholesterol and phytosterol absorption impacts the risk of coronary artery disease (CAD) using as instruments sequence variants in the ABCG5/8 genes, key regulators of […]

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Getting the COVID-19 pandemic into perspective: a nursing imperative.

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As we approach the seventh month of the latest pandemic to wreak havoc and death across all societies, it beggars belief that many world and national leaders have acted surprised […]

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Evolution of effective serial interval of SARS-CoV-2 by non-pharmaceutical interventions.

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Studies of novel coronavirus disease (COVID-19) have reported varying estimates of epidemiological parameters such as serial intervals and reproduction numbers. By compiling a unique line-list database of transmission pairs in […]

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Use of short-acting opioids in the management of breathlessness: an evidence-based review.

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To provide an evidence-based review on the use of short-acting opioids for management of breathlessness in patients with advanced diseases.We identified 28 randomized controlled trials that examined the effect of […]

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Prognostic value of Cardiac Biomarkers in COVID-19 Infection: A Meta-analysis.

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Background Multiple Biomarkers have recently been shown to be elevated in COVID-19, a respiratory infection with multi-organ dysfunction; however, information regarding the prognostic value of cardiac biomarkers as it relates […]

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99mTc-Leukocyte Scintigraphy Revealed Viral Pulmonary Infection in a COVID-19 Patient.

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Tc-leukocyte scintigraphy was performed on a 40-year-old woman with spiking fevers. A focus of intense uptake in the right upper thorax was identified, concerning for infection along the central line […]

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Estimated Community Seroprevalence of SARS-CoV-2 Antibodies – Two Georgia Counties, April 28-May 3, 2020.

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Transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is ongoing in many communities throughout the United States. Although case-based and syndromic surveillance are critical for monitoring the […]

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